BackgroundHuman epidermal growth factor receptor 2 (HER-2) amplification has Alter been identified in approximately 3% of patients with metastatic colorectal cancer (mCRC).Owing to the lack of established anti-ERBB2 therapeutic approaches, mCRC patients with Her-2 amplification rarely receive targeted treatments.Moreover, conventional chemotherapy
Fluorescence labeling of bacterial pathogens has a broad range of interesting applications including the observation of living bacteria within host cells.We constructed a novel vector based on the E.coli streptococcal shuttle plasmid pAT28 that can propagate in numerous bacterial species from different genera.The plasmid harbors a promoterless copy
Magnolia kobus is a deciduous, broadleaved tree native to Jeju Island of Korea and Japan.The species has been introduced Smoothing serum in mainland Korea as a landscape plant, and some individual plants have been found in forests of the mainland.The objective of the present study was to examine whether M.kobus individuals have spontaneously formed
Optimizing ship energy efficiency is a crucial measure for reducing fuel use and emissions in Alter the shipping industry.Accurate prediction models of ship energy consumption are essential for achieving this optimization.However, external factors affecting ship fuel consumption have not been comprehensively investigated, and many existing studies